WHAT’S BEING CLAIMED:
- Researchers at the University of Aberdeen developed a new drug that can melt away the fat that clogs the arteries.
- The drug was originally designed to fight diabetes and cancer.
- Now, scientists are hoping to test the new drug on humans.
A new drug that was tested in mice was found to dissolve fat deposits and plaque that clog the arteries, researchers say. They also claim that the miracle drug Trodusquemine can fully reverse the effects of Atherosclerosis in just a single dose.
Atherosclerosis is the build-up of fatty plaque inside the arteries. Fat and cholesterol are usually the culprits of plaque build-up. In the long run, clogged arteries can cause a number of different heart problems and can lead to heart attacks and strokes.
According to Mirela Delibegovic, everyone has some level of fatty streaks in their arteries which develop further with age. Delibegovic is a professor at the University of Aberdeen who helped lead the study.
The research team tested mice and discovered that those given either a single a dose or a regular treatment of Trodusquemine, turned to have less fatty plaques in their arteries.
“These have only been tested at pre-clinical level, in mice, so far but the results were quite impressive and showed that just a single dose of this drug seemed to completely reverse the effects of atherosclerosis,” Delibegovic said.
She also said that the next step is to do human testing.
Trodusquemine is already undergoing separate testing to treat breast cancer and diabetes, where it inhibits an enzyme called PTP1B.
What the team discovered was that it also stimulated the action of another protein, AMP-activated protein kinase (AMPK). It effectively mimics exercise and reduces chronic inflammation.
The British Heart Foundation funded the study for £236,000 ($308,000) to further investigate the drug’s effect on Atherosclerosis.