New hope for burn patients: Machine creates new skin


  • A new machine called denovoGraft is capable of developing new skin that could cater burn patients.
  • Built by CUTISS developers, the denovoGraft can create several skin grafts in just one go.
  • The treatment is still in phase II trial; phase III trial would end in 2024.

A new invention features a phenomenal machine that could create a new skin for burn patients. With just a tiny piece of skin, the machine can transform it into a new skin with the size of a manhole cover using a bioengineering technology.

The machine, created by developers from the CUTISS, was built as a solution for millions of people who suffered and are experiencing burns. Called denovoGraft, the machine is just the same size as a coffee table.

The process begins by using healthy, undamaged skin cells that were extracted from a patient. These would be nurtured in a lab then will be mingled with hydrogel. With an output of about 1mm inch thick skin, it would be tantamount to the combined width of an individual’s natural skin layers.

Even though the machine is still in phase II trials, it is already being used as a treatment for a few people with rare conditions. This skin crafting approach is more sophisticated, hence it’s only the available avenue for them as of the moment.

“At the moment we can multiply the surface area of the original sample by a factor of 100, and we’re aiming eventually for a factor of 500,” said CUTISS co-founder and director Daniela Marino.

The denovoGraft could produce several grafts everytime sans manual input, which could significantly cut production costs and timings.

Currently, there are only roughly 40 people working full-time in the skin reconstruction industry. The market for this kind of treatment is valued at below $2 billion.

“There are 20 centres of excellence in Europe for treating serious burns,” Marino told Swiss Info. “We’re going to start by working with them, and we can do that on our own. Later, sure, we’ll have to find partners.”

Marino noted that the phase III trials would be done by 2024. After that, initial launching of the treatment would be largely available in Europe.

Based on a Swiss news report, about 11 million people across the world are suffering from severe burns yearly. The invention of denovoGraft could help address this health crisis that has long been in dire need of an advanced, more comprehensive treatment.

Source: Good News Network

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